Preferential expression of PAPPA in human preadipocytes from omental fat
نویسندگان
چکیده
منابع مشابه
Expression Profiling of Omental Fat in PCOS
39 40 Context The polycystic ovary syndrome (PCOS) is frequently associated with visceral obesity, suggesting 41 that omental adipose tissue might play an important role in the pathogenesis of the syndrome. 42 Objective To the study of the expression profiles of omental fat biopsies obtained from morbidly obese 43 women with or without PCOS at the time of bariatric surgery. 44 Design Case-contr...
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Lipodystrophy with increased intra-abdominal fat in human immunodeficiency virus (HIV) infection is common in the era of highly active antiretroviral therapy. It contributes to the metabolic derangements, as it does in non-HIV-related conditions. Growth hormone administration reduces intra-abdominal fat content. This study compared the relative changes in omental-mesenteric (OMAT) and retroperi...
متن کاملFat depot-specific characteristics are retained in strains derived from single human preadipocytes.
Fat depots vary in size, function, and potential contribution to disease. Since fat tissue turns over throughout life, preadipocyte characteristics could contribute to this regional variation. To address whether preadipocytes from different depots are distinct, we produced preadipocyte strains from single abdominal subcutaneous, mesenteric, and omental human preadipocytes by stably expressing h...
متن کاملIncreased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes.
Site differences in adipose tissue function may have implications for insulin-resistant conditions. In mature adipose tissue, subcutaneous adipocytes have higher leptin secretion, similar tumor necrosis factor (TNF)-alpha secretion, and lower catecholamine-stimulated lipolysis as compared with omental adipocytes. In this study, lipolysis and leptin and TNF-alpha secretion were compared between ...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2014
ISSN: 0022-0795,1479-6805
DOI: 10.1530/joe-13-0610